EtEraser™ SE Endotoxin Removal Kit
EtEraser™ SE Endotoxin Removal Kit
1. Zambiri zamalonda
Lipopolysaccharide (LPS) ndi bakiteriya endotoxin ndi gawo lalikulu la makoma a cell a mabakiteriya a gramnegative.Recombinant protein kuchokera ku E.coli nthawi zambiri imakhala ndi ma endotoxins ambiri.Kuchotsa maendotoxins awa ndikofunikira kwambiri pamayendedwe akumunsi.
EtEraser SE Endotoxin Removal zidaadapangidwa kuti achotse kuipitsidwa kwa endotoxin ku njira zamadzi.Ma kits okhala ndi utomoni wochotsa utomoni amamanga kuti achepetse kuchuluka kwa endotoxin mu zitsanzo zamapuloteni ndi≥99% pasanathe maola awiri.
Chidacho chimaphatikizapo chigawo chochotsa endotoxin chodzaza kale ndi 1.5 ml, Buffer Equilibration, Regeneration Buffer ndi chubu la pyrogen-freecollection ndi malangizo.Mzerewu uli ndi mphamvu yomangirira kwambiri> 2,000, 000 EU / ml.Izi zitha kugwiritsidwanso ntchito mpaka kasanu ngati zitapangidwanso bwino.The affinity resin imapezeka mu slurry ndipo ikhoza kukhala up-scalingin biopharmaceutical process.
EtEraser SE Endotoxin Removal zidaimagwiritsa ntchito chakudya chosinthidwaε-poly-L-lysineashigh affinity ligand kwa endotoxins.Utoto ndi mikanda ya agarose yomwe imakhala yokhazikika kwambiri ndipo ilibe mphamvu ya cytotoxic m'thupi la munthu.Pambuyo pa kuyeretsedwa, sipadzakhala zotsalira zapoizoni zotsalira mu zitsanzo.Izizida zochotsera endotoxinitha kugwiritsidwa ntchito mu mankhwala a protein, katemera, ma antibodies, DNA/RNA, polysaccharide ndi zitsanzo zina zamoyo.
2. Zogulitsa
• kukhazikika kwakukulu - sikumakhudza ntchito za zitsanzo zambiri za sayansi
• mphamvu zomangira zambiri — >2000000 EU/ml
• sanali poizoni --> Non-poizoni chakudya kalasi ligands, palibe cytotoxic zotsatira poly lysine
• kuchira kwa protein yambiri - > 95% kuchira kwa mapuloteni kwa zitsanzo za mapuloteni
• Kuchotsa kwakukulu - chotsani > 99% endotoxin, mlingo wa endotoxin mu chitsanzo ukhoza kukhala wochepera 0.1 EU/ml pambuyo pochotsa endotoxin
• osiyanasiyana ntchito - angagwiritsidwe ntchito pochotsa endotoxin kwa mapuloteni, peptides, chitetezo, katemera, polysaccharide ndi zina biological zitsanzo.